These HILIC columns, featuring unbonded BEH substrate, are optimized for efficient, reproducible separation of very polar compounds under HPLC HILIC conditions. They provide alternative selectivity to traditional reversed-phase columns, enhancing peak shape, retention, and column lifetime, establishing a new standard for HILIC separations.
- Separates and retains very polar compounds efficiently.
- Optimized for reproducible HPLC HILIC conditions.
- More rugged and chemically stable than silica-based HILIC phases.
- Extends column lifetime significantly.
- Offers alternative selectivity to reversed-phase columns.
- Enhances peak shape and retention for polar analytes.
- Utilizes complex retention mechanisms (partitioning, ion exchange, hydrogen bonding).
- Functions with mobile phases over 80% acetonitrile.
- Enables orthogonal separations via elution reversal.